PHOENIX - Claudio Vargas threw six solid innings and Luis Gonzalez scored the go-ahead run after hitting his 534th career double, helping the Arizona Diamondbacks beat Andy Pettitte and the Houston Astros 4-3 Sunday.
Carlos Quentin's broken-bat single brought Gonzalez home from third to break a 2-2 tie in the sixth as the Diamondbacks salvaged the third game of the series.
Gonzalez led off the inning with a double into the right-field corner to tie Lou Gehrig for 26th on the career doubles list. Conor Jackson moved Gonzalez to third with a sacrifice bunt.
Eric Byrnes homered for the second consecutive game for Arizona, his team-leading 18th of the season. The 440-foot solo shot to left-center with two outs in the seventh made it 4-2.
Vargas (9-8), who threw a season-high 113 pitches, gave up a two-run homer to Lance Berkman in the first, then blanked the Astros for the next five innings. He allowed six hits, struck out six, walked two and hit a batter in his only his third victory in his last 11 starts.
Luis Vizcaino and Tony Pena each pitched a scoreless inning before Jorge Julio entered in the ninth for the Diamondbacks. He allowed Aubrey Huff's run-scoring single before he struck out Morgan Ensberg with runners on first and third for his 14th save in 17 tries.
Pettitte (10-12), 1-5 against Arizona in his career, gave up four runs and eight hits in 7 1-3 innings. He struck out six and walked one.
Stephen Drew was 2-for-3 with a double and made a spectacular play to rob Pettitte of a hit in the fifth. The rookie shortstop made a diving stop to his left, then threw the runner out from his knees.
Willy Taveras led off the game with a single, then Adam Everett reached on a fielder's choice. Berkman followed, and hit a 3-0 pitch 414 feet, just above the home-run line in straightaway center, his 30th homer of the season.
The Diamondbacks tied it at 2 in the third. Chris Snyder drew a leadoff walk, then Drew doubled off the wall in left to put runners at second and third with no outs. Vargas' broken-bat groundout brought home Snyder, then with two outs, Damion Easley's sharp grounder took a bad bounce at third for a base hit that scored Drew.
Vargas escaped a jam in the third after Ensberg walked and Luke Scott singled to start the inning. The Diamondbacks failed to convert Chris Burke's grounder into a double play, but got the out at second while Ensberg went to third with one out. He was stranded when Brad Ausmus hit into a double play.
The Astros loaded the bases in the fourth, thanks to Vargas' throwing error that would have been the third out. But Ensberg grounded out to end the threat. Arizona also turned a double play to escape the seventh.
Notes:@ Arizona OF Jeff DaVanon, who sprained his left ankle sliding into second Saturday night, is expected to be sidelined for at least two games. ... The Diamondbacks again have no left-handers on their staff after designated LHP Randy Choate for assignment. ... Gonzalez leads the NL with 39 doubles. ... Houston scored 17 runs in the first two games of the series.